Efficacy and Safety of Intraocular Pressure-Lowering Agents Bimatoprost and Timolol Maleate in Glaucoma

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Safety and Efficacy of Fixed Combination Travoprost-Timolol in the Lowering of Intraocular Pressure

The fixed combination eye drop Duotrav is a combination of travoprost 0.004% and timolol maleate 0.5%. Both travoprost and timolol have been used separately for the treatment of glaucoma by lowering intraocular pressure. Multiple studies have demonstrated the efficacy and safety of the fixed combination travoprost/timolol for the treatment of open-angle glaucoma and ocular hypertension. The onc...

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Safety and efficacy of bimatoprost 0.03% versus timolol maleate 0.5%/dorzolamide 2% fixed combination.

PURPOSE To determine the efficacy and safety of bimatoprost given every evening versus the dorzolamide/timolol fixed combination (DTFC) given twice daily in open-angle glaucoma and ocular hypertensive patients. METHODS A double-masked, three-center, prospective, randomized, crossover comparison with two 8-week treatment periods following a 4-week medicine free washout period. Diurnal curve in...

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The intraocular pressure lowering efficacy of 0.5% timolol maleate versus 1% brinzolamide in cases of primary open angle glaucoma and ocular hypertension

Objectives: The aim of this study was to compare the intraocular pressure lowering efficacy of timolol maleate with brinzolamide in cases of primary open angle glaucoma and ocular hypertension. Methods and Materials: This prospective, open, randomized, parallel group, comparative study was conducted in patients coming to the Department Of Ophthalmology, Rajindra Hospital attached to Government ...

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Efficacy and safety of fixed-combination bimatoprost/timolol ophthalmic solution

and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, pleas...

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Effect of preservative removal from fixed-combination bimatoprost/timolol on intraocular pressure lowering: a potential timolol dose-response phenomenon.

PURPOSE Many patients with glaucoma require combination therapies to achieve target intraocular pressure (IOP) and preserve visual function. Ocular hypotensives often contain a preservative (eg, benzalkonium chloride [BAK]), but preservative-free (PF) formulations have been developed for patients with sensitivity. A Phase III study found the efficacy of bimatoprost 0.03%/timolol 0.5% (bim/tim, ...

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ژورنال

عنوان ژورنال: International Journal of Pharmacology

سال: 2018

ISSN: 1811-7775

DOI: 10.3923/ijp.2018.179.186